The forced swim test: Giving up on behavioral despair (Commentary on Molendijk & de Kloet, 2021)
نویسندگان
چکیده
منابع مشابه
The mouse forced swim test.
The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs, antidepressant efficacy of new compounds, and experimental manipulations that are aimed at rendering or preventing depressive-like states. Mice are placed in an inescapable transparent tank that is filled with water and their escape related mobility behavior is measured. The forced swim test is straigh...
متن کاملImpact of maternal melatonin suppression on forced swim and tail suspension behavioral despair tests in adult offspring
Melatonin is an essential hormone, which regulates circadian rhythms and has antioxidative and anticarcinogenic effects. As melatonin secretion is suppressed by light, this effect was examined on the offspring of the Wistar rat females exposed to continuous light (500 lux) during the second half of the pregnancy (day 12 to 21). Control rats were kept under a 12:12 light-dark cycle. The resulted...
متن کاملutomated behavioral analysis of limbs ’ activity in the forced swim test oman
The forced swim test in rodents has been widely used to evaluate potential effectiveness of antidepressant medications since it was described in 1977 by Porsolt. In this test, a rodent is placed in a water container, and its immobility time is measured. The immobility time indicates the level of inactivity, interpreted as ‘hopelessness’, and has been shown to decrease when the rodent is treated...
متن کاملthe relationship between eq, iq and test format: a study on test fairness
the major aim of this study was to investigate the relationship between iq, eq and test format in the light of test fairness considerations. this study took this relationship into account to see if people with different eq and iq performed differently on different test formats. to this end, 90 advanced learners of english form college of ferdowsi university of mashhad were chosen. they were ask...
15 صفحه اولInfluence of enrichment on behavioral and neurogenic effects of antidepressants in Wistar rats submitted to repeated forced swim test
Repeated forced swimming test (rFST) may detect gradual effects of antidepressants in adult rats. Antidepressants, as enrichment, affected behavior and neurogenesis in rats. However, the influence of enrichment on behavioral and neurogenic effects of antidepressants is unknown. Here, effects of antidepressants on rFST and hippocampal neurogenesis were investigated in rats under enriched conditi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2021
ISSN: 0953-816X,1460-9568
DOI: 10.1111/ejn.15270